The elements which are particularly reactive need to be handled carefully. Those include the alkali metals and the halogens. Some gases and heavy metals are toxic and need special handling. Clearly, radioactive elements require shielding or avoidance.
Handling instructions may be found on the MSDS forms for each element.
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What counts as "special"?
The alkali metals (and some allotropes of P) must not be exposed to air.
The gaseous elements must be kept in containers made for the purpose.
The liquid elements must be kept in a closed container lest they evaporate.
All the elements with atomic numbers greater than 83 and Tc need to be shielded because of the danger from radioactivity.
If you're going to use Sn for anything with structural strength, it must always be kept at a temperature above 13.2°C.
all of them need special handling
The elements which are particularly reactive need to be handled carefully. Those include the alkali metals and the halogens. Some gases and heavy metals are toxic and need special handling. Clearly, radioactive elements require shielding or avoidance.
Handling instructions may be found on the MSDS forms for each element.
https://www.acialloys.com/element-msds/
Uranium definitely.